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干燥综合征患者慢性化脓性腮腺炎的保守治疗:病例系列

Conservative Management of Chronic Suppurative Parotitis in Patients with Sjögren Syndrome: A Case Series.

作者信息

Bukhari Alaa F, Bugshan Amr S, Papas Athena, Desai Bhavik, Farag Arwa M

机构信息

Department of Oral Diagnostic Sciences, Division of Oral Medicine, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.

Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

Am J Case Rep. 2021 Mar 19;22:e929553. doi: 10.12659/AJCR.929553.

Abstract

BACKGROUND Parotitis is an inflammation of the parotid gland, which can be caused by factors including infection, radiation, and hyposalivation secondary to systemic conditions, such as Sjögren syndrome, rheumatoid arthritis, or medication. Bacterial parotitis is a rare complication that can be observed in patients with hyposalivation. However, it is also observed in elderly and immunocompromised patients. Lack of continuous flushing of salivary glands and their ducts due to decreased salivary flow renders the glands prone to retrograde colonization with oral microflora. Several microorganisms have been associated with bacterial infections of the parotid glands; Staphylococcus aureus is the most common, accounting for 80% of cases, followed by mixed bacterial communities, including streptococci, anaerobes, and gram-negative bacilli. Bacterial parotitis presents as tenderness, swelling, and purulent sialorrhea from the salivary gland's duct. Immediate administration of broad-spectrum antibiotics, based on the results of the patient's culture and sensitivity test, has shown success in treating these cases. CASE REPORT We report 3 cases of chronic suppurative parotitis secondary to dry mouth and due to Sjögren syndrome that did not respond to oral or intravenous antibiotics and was successfully managed using conservative methods, such as the local application of superficial moist heat and periodic pus drainage by manipulating the parotid glands at dental clinics. CONCLUSIONS We concluded that conservative approaches, such as massaging the glands, local application of superficial moist heat, and periodic pus drainage without using antibiotics, should be considered as the first-line management of bacterial infection of the parotid glands.

摘要

背景

腮腺炎是腮腺的炎症,其可由多种因素引起,包括感染、辐射以及继发于系统性疾病(如干燥综合征、类风湿性关节炎或药物)的唾液分泌减少。细菌性腮腺炎是一种罕见的并发症,可在唾液分泌减少的患者中观察到。然而,在老年人和免疫功能低下的患者中也有发现。由于唾液流量减少,唾液腺及其导管缺乏持续冲洗,使得腺体易于被口腔微生物逆行定植。几种微生物与腮腺的细菌感染有关;金黄色葡萄球菌最为常见,占病例的80%,其次是包括链球菌、厌氧菌和革兰氏阴性杆菌在内的混合细菌群落。细菌性腮腺炎表现为腮腺导管处压痛、肿胀及脓性涎液外流。根据患者的培养和药敏试验结果立即给予广谱抗生素,已证明在治疗这些病例中取得成功。病例报告:我们报告3例继发于口干且由干燥综合征引起的慢性化脓性腮腺炎,这些病例对口服或静脉用抗生素均无反应,通过保守方法成功治疗,如局部应用浅表湿热敷以及在牙科诊所通过手法操作腮腺进行定期排脓。结论:我们得出结论,保守方法,如按摩腺体、局部应用浅表湿热敷以及不使用抗生素的定期排脓,应被视为腮腺细菌感染的一线治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73ac/7988433/3a87aba29e99/amjcaserep-22-e929553-g001.jpg

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