RhoGAP: the next big thing for small mice?
作者信息
Birnbaum Morris J
机构信息
Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA.
出版信息
Dev Cell. 2002 May;2(5):521-3. doi: 10.1016/s1534-5807(02)00183-1.
Abstract
The size of an organism is determined by the number and size of its constituent cells. The insulin/IGF-1 signaling systems have been long recognized to play a critical role in the determination of body size. Now the generation of mice deficient for a RhoGAP suggests that this small G protein might also regulate the growth of animals.
摘要
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