Chakera T M, Howarth F H, Kendall M J, Lawrence D S, Whitfield A G
Clin Radiol. 1975 Oct;26(4):455-9. doi: 10.1016/s0009-9260(75)80095-x.
In a study of 42 patients with ankylosing spondylitis, upper lobe fibrosis was present in six (14-3%) patients. All the patients with upper lobe fibrosis had total spinal ankylosis, and half showed peripheral joint involvement. A further 13 patients (30-9%) had other focal pulmonary abnormalities compared with only six (14-3%) of a group of age-matched controls. There was no correlation between the radiological extent of the disease (spinal changes and pulmonary involvement) and any of the haematological or biochemical parameters measured. Treatment with radiotherapy was not responsible for these changes.
在一项针对42例强直性脊柱炎患者的研究中，6例（14.3%）患者存在上叶纤维化。所有上叶纤维化患者均有脊柱完全强直，半数患者有外周关节受累。另有13例患者（30.9%）有其他局灶性肺部异常，而在一组年龄匹配的对照组中，这一比例仅为6例（14.3%）。疾病的放射学范围（脊柱改变和肺部受累）与所测量的任何血液学或生化参数之间均无相关性。放射治疗并非导致这些改变的原因。
