Liao Q, Zhou J
Department of Orthopedics, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Hunan Yi Ke Da Xue Xue Bao. 1999;24(3):279-81.
Twelve cases of ossifying fibroma of long bones, the lesions in 11 cases were resected with their sclerotic margin. Inactivation of the tumor cells within bone cavity was applied 50% Zinc Chloride, and autogenous bone grafts were applied with or without a few man-made bones. One case was treated by en bloc resection of the lesion. Follow-up for 3-14 years revealed that 2 cases recurred, and secondary operation was performed. After that follow-up for 5-14 years revealed no-recurrence. Recurrence rate of these cases was low and the effect of treatment was satisfactory. This kind of lesion showed the features of its aggressive growth and proneness to recur after operation. The authors consider that resection of the lesion including its sclerotic margin was effective to prevent recurrence.
12例长骨骨化性纤维瘤,11例病变连同其硬化边缘一并切除。用50%氯化锌对骨腔内的肿瘤细胞进行灭活处理,并应用自体骨移植,部分病例加用少量人工骨。1例采用病变整块切除。随访3至14年,2例复发并再次手术,再次手术后随访5至14年无复发。这些病例的复发率低,治疗效果满意。此类病变呈侵袭性生长,术后易复发。作者认为,切除病变连同其硬化边缘可有效预防复发。