D2淋巴结清扫术可提高腹膜细胞学检查阳性的胃癌患者的生存率。
D2-lymphadenectomy improves the survival of patients with peritoneal cytology-positive gastric cancer.
作者信息
Inada Takao, Ogata Yoshiro, Kubota Tetsuro, Ishihara Masami, Tomikawa Moriaki, Ando Jiro, Ozawa Iwao, Hishinuma Shoichi, Shimizu Hideaki, Kotake Kenjiro
机构信息
Department of Surgery, Tochigi Cancer Center, Utsunomiya, Japan.
出版信息
Anticancer Res. 2002 Jan-Feb;22(1A):291-4.
BACKGROUND
According to the current Japanese Classification of Gastric Cancer, patients with peritoneal cytology-positive (CY1) gastric cancer are classified as stage IV and the curative potential of resection for these patients is regarded as non-curative.
MATERIALS AND METHODS
We compared the clinical outcome of CY1 patients (n=55) with those of patients with other non-curative factors (n=87), to clarify the optimal surgical strategy for CY1 patients.
RESULTS
The 5-year survival rate of CY1 patients was 10.8%, which was significantly better than that observed in the patients with the other non-curative factors. Among CY1 cases, survival outcome of the patients with lymph node metastasis limited to within group 2 was significantly better than the patients with group 3 lymph node metastasis.
CONCLUSION
These results suggested that gastrectomy combined with extended lymphadenectomy should be recommended for patients with gastric cancer who have positive peritoneal cytology as the only non-curative factor.
背景
根据当前日本胃癌分类，腹膜细胞学阳性（CY1）的胃癌患者被归类为IV期，这些患者的手术切除治愈潜力被认为无法治愈。
材料与方法
我们比较了CY1患者（n = 55）与其他非治愈因素患者（n = 87）的临床结局，以明确CY1患者的最佳手术策略。
结果
CY1患者的5年生存率为10.8%，显著高于其他非治愈因素患者。在CY1病例中，淋巴结转移局限于第2组的患者生存结局明显优于有第3组淋巴结转移的患者。
结论
这些结果表明，对于仅腹膜细胞学阳性这一非治愈因素的胃癌患者，应推荐行胃切除术联合扩大淋巴结清扫术。
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