[用凝血酶、N-乙酰凝血酶或胰蛋白酶灌注离体肾脏后抗凝系统的状态]

[The state of the anticoagulant system following perfusion of the isolated kidney with thrombin, N-acetyl-thrombin or trypsin].

作者信息

Kudrashov B A, Baskova I P, Kalishevskaia T M, Mirkamalova E G, Orlova A S

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1975 Nov;61(11):1670-4.

PMID:1201792

Abstract

Tripsine perfused through the rabbit humorally isolated kidney with preserved innervation evokes, like the thrombin, an activation of the second anticoagulating system (SAS). N-acetyl-thrombin lacking in coagulating effect due to blockade of free aminogroups, did not evoke the activation of the SAS under the same conditions.

摘要

用胰蛋白酶灌注家兔经体液隔离且神经支配保存完好的肾脏时，会像凝血酶一样引发第二种抗凝系统（SAS）的激活。因游离氨基被封闭而缺乏凝血作用的N-乙酰凝血酶，在相同条件下不会引发SAS的激活。