Floody Owen R
Department of Psychology, Bucknell University, Lewisburg, Pennsylvania 17837, USA.
Horm Behav. 2002 Jun;41(4):366-76. doi: 10.1006/hbeh.2002.1776.
Previous studies suggest that ultrasound production by female hamsters is better able than other reproductive behaviors to recover from an initial drop caused by damage to the ventromedial hypothalamus (VMN). At the same time, few studies have examined the time course of such lesion effects. To remedy this, female hamsters were observed before and after control operations or VMN lesions. The behaviors considered were ultrasound production, lordosis, approach, and vaginal marking. Ultrasound production, lordosis, and approach were affected by lesions, permitting the description of the time course of each of these effects. Only ultrasound rates showed evidence of recovery, which culminated in rates significantly above those observed preoperatively in the same animals. This suggests that ultrasound production is unusual in its response to VMN damage and that the underlying mechanism could be of interest in studies of the processes that determine recovery from brain damage.
先前的研究表明，雌性仓鼠发出超声波的行为相较于其他繁殖行为，更能从腹内侧下丘脑（VMN）损伤导致的最初下降中恢复过来。与此同时，很少有研究考察这种损伤效应的时间进程。为了弥补这一点，在进行对照手术或VMN损伤前后对雌性仓鼠进行了观察。所考虑的行为包括发出超声波、脊柱前凸、接近和阴道标记。发出超声波、脊柱前凸和接近行为受到损伤的影响，从而能够描述这些效应各自的时间进程。只有超声波发出频率显示出恢复的迹象，最终显著高于同一动物术前观察到的频率。这表明发出超声波的行为在对VMN损伤的反应方面不同寻常，其潜在机制可能在决定从脑损伤中恢复的过程研究中具有重要意义。
