Salazar Cabrera Carmen, de Saa Alvarez Md Ma del Rosario, Aparicio Pérez Magdalena Sofía, Marcos Calle José, García García Benjamín
E.N.T. Department, Hospital San Pedro de Alcántara, Cáceres, SPAIN.
Am J Otolaryngol. 2002 May-Jun;23(3):169-72. doi: 10.1053/ajot.2002.123454.
Myasthenia gravis is a motor neuron disease caused by the presence of antibodies against acetylcholine receptors that interfere with the proper function of the neuromuscular junction. Twenty percent of patients with myasthenia gravis present some type of bulbar deficits such as rhinolalia, dysphagia or dysphonia as the first symptom of disease. We report 5 patients with deficits that illustrate different aspects of the disease. Our role as otolaryngologists is to establish a diagnosis or to provide a solution for the respiratory failure caused by chronic aspiration.
重症肌无力是一种运动神经元疾病，由抗乙酰胆碱受体抗体的存在引起，这些抗体会干扰神经肌肉接头的正常功能。20%的重症肌无力患者会出现某种类型的延髓功能障碍，如鼻音、吞咽困难或发音障碍，作为疾病的首发症状。我们报告了5例有这些功能障碍的患者，这些病例展示了该疾病的不同方面。我们耳鼻喉科医生的职责是做出诊断，或为慢性误吸导致的呼吸衰竭提供解决方案。
