Koga Y, Hayashida Y, Ikeda K, Inokuchi K, Hashimoto N
J Pediatr Surg. 1975 Dec;10(6):949-53. doi: 10.1016/s0022-3468(75)80101-1.
Experimental ileal atresia and stenosis were produced by a localized ligation of the mesenteric vessels in fetuses from 13 pregnant mongrel dogs having gestational ages of 45-55 days. The intestinal infarct in the fetus was characterized by an aseptic coagulation necrosis selectively limited to the mucosa and submucosa, and also by intense hyperemia and minimal cellular reaction in the adjacent tissue. Eleven days after the devascularization, type 2 intestinal atresia, in which there is a long cord between the blunt ends microscopically similar to that seen in humans.
通过对13只妊娠45 - 55天的杂种犬胎儿的肠系膜血管进行局部结扎，制造出实验性回肠闭锁和狭窄。胎儿肠道梗死的特征为无菌性凝固性坏死，选择性地局限于黏膜和黏膜下层，还表现为相邻组织的强烈充血和轻微细胞反应。去血管化11天后，出现2型肠闭锁，在显微镜下，钝端之间有一条长索，类似于人类所见的情况。
