Suppr超能文献

冠状动脉分流术可减少非体外循环冠状动脉手术期间术中短暂性心肌功能障碍。

Intracoronary shunts reduce transient intraoperative myocardial dysfunction during off-pump coronary operations.

作者信息

Yeatman Mark, Caputo Massimo, Narayan Pradeep, Ghosh Arup Kumar, Ascione Raimondo, Ryder Ian, Angelini Gianni D

机构信息

Bristol Heart Institute, University of Bristol, United Kingdom.

出版信息

Ann Thorac Surg. 2002 May;73(5):1411-7. doi: 10.1016/s0003-4975(02)03407-0.

Abstract

BACKGROUND

This study investigated the hemodynamic changes in patients undergoing multiple vessel beating heart coronary revascularization in the presence or absence of an intracoronary shunt.

METHODS

Forty patients were randomized to off-pump with a shunt (n = 20) or with the proximal coronary artery occluded by a soft snare (n = 20). Hemodynamic measurements were recorded at base line, during construction, and after completion of each distal anastomosis.

RESULTS

Grafting of the left anterior descending coronary artery anastomosis was associated with a significant decrease in stroke volume, cardiac index, and mean arterial pressure, and an increase in pulmonary capillary wedge pressure and systemic vascular resistance in the snare but not in the shunt group. During grafting of the posterior descending coronary artery there was a marked decrease in stroke volume and cardiac index, and an increase in central venous pressure in both groups, and an increase in heart rate, mean pulmonary arterial pressure, pulmonary capillary wedge pressure, and systemic vascular resistance only in the snare group. The most extensive changes were observed during the circumflex coronary artery anastomosis with a reduction in stroke volume, cardiac index, and mean arterial pressure, and an increase in central venous pressure, pulmonary capillary wedge pressure, pulmonary arterial pressure, and systemic vascular resistance in both groups. In all settings, these changes were transient and recovered after the heart was returned to its anatomical position in the shunt group, whereas stroke volume and cardiac index remained reduced, and systemic vascular resistance was elevated in all settings in the snare group.

CONCLUSIONS

Stabilization of the left anterior descending coronary artery to perform the anastomosis resulted in temporary hemodynamic changes, which are prevented by the use of an intracoronary shunt. The hemodynamic deterioration during the construction of the posterior descending coronary artery and circumflex coronary artery anastomoses is transient in the shunt group, whereas the snaring technique is associated with an impairment of early functional recovery.

摘要

背景

本研究调查了在有或无冠状动脉内分流装置的情况下,接受多支血管不停跳冠状动脉血运重建术患者的血流动力学变化。

方法

40例患者被随机分为使用分流装置的非体外循环组(n = 20)和使用软圈套器阻断近端冠状动脉的非体外循环组(n = 20)。在基线、每个远端吻合口构建期间及完成后记录血流动力学测量值。

结果

在圈套器组而非分流装置组中,左前降支冠状动脉吻合口移植与每搏量、心脏指数和平均动脉压显著降低,以及肺毛细血管楔压和全身血管阻力增加有关。在右后降支冠状动脉移植期间,两组的每搏量和心脏指数均显著降低,中心静脉压升高,仅圈套器组的心率、平均肺动脉压、肺毛细血管楔压和全身血管阻力增加。在左旋支冠状动脉吻合期间观察到最广泛的变化,两组的每搏量、心脏指数和平均动脉压降低,中心静脉压、肺毛细血管楔压、肺动脉压和全身血管阻力增加。在所有情况下,这些变化都是短暂的,在分流装置组中,心脏恢复到解剖位置后恢复,而在圈套器组中,所有情况下每搏量和心脏指数仍降低,全身血管阻力升高。

结论

稳定左前降支冠状动脉以进行吻合会导致暂时的血流动力学变化,冠状动脉内分流装置的使用可防止这种变化。在分流装置组中,右后降支冠状动脉和左旋支冠状动脉吻合构建期间的血流动力学恶化是短暂的,而圈套技术与早期功能恢复受损有关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验