Suppr超能文献

用于组合化学的固体载体

Solid supports for combinatorial chemistry.

作者信息

Yu Zhanru, Bradley Mark

机构信息

Combinatorial Centre of Excellence, Department of Chemistry, University of Southampton, Highfield, SO17 1BJ, Southampton, UK.

出版信息

Curr Opin Chem Biol. 2002 Jun;6(3):347-52. doi: 10.1016/s1367-5931(02)00327-7.

Abstract

Over the past year, numerous techniques have been used to study the resins commonly utilised in solid-phase synthesis to allow a greater understanding of the chemical nature and the physical properties of the supports. In addition, to overcome some of the drawbacks of existing materials, several new resins and new methods of handling solid supports have been developed. New methodologies have also been introduced to simplify the preparation of solid supports.

摘要

在过去的一年里,人们运用了多种技术来研究固相合成中常用的树脂,以便更深入地了解载体的化学性质和物理特性。此外,为了克服现有材料的一些缺点,已经开发了几种新型树脂和处理固体载体的新方法。还引入了新的方法来简化固体载体的制备。

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