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[鸟枪弹样视网膜脉络膜病变。五例临床病例分析]

[Birdshot retinochoroidopathy. Five clinical cases analysis].

作者信息

Abrantes P, Martins M, Ferreira P, Ganhão F

机构信息

Servicio de Oftalmología, Hospital de S o José, Lisboa, Portugal.

出版信息

Arch Soc Esp Oftalmol. 2002 May;77(5):247-55.

PMID:12023743
Abstract

PURPOSE

The Birdshot retinochoroidopathy is a rare chronical intraocular inflammatory disease. The authors made a comparative study of the disease's clinical manifestations and its response to therapy.

METHODS

We selected five patients who had ocular inflammation which presented on the ocular fundus examination typical multifocal yellow-white patches of depigmentation of choroid and pigment epithelium and vitreous inflammation.

RESULTS

All the patients showed early spots of hypofluorescence that became hyperfluorescent in the venous phase of angiography, a depression of b-wave amplitude of electroretinogram, a blue-yellow defect of colour vision and carried HLA-A 29 antigen. We recorded an improvement of the visual acuity and of the clinical picture after treatment with corticosteroid and cyclosporine A.

CONCLUSION

Even though Birdshot retinochoroidopathy is a rare pathology in Southern Europe, the cases presented allowed us to conclude that early diagnosis and appropriate therapy greatly improve the well being of these patients (Arch Soc Esp Oftalmol 2002; 77: 247-256).

摘要

目的

鸟枪弹样视网膜脉络膜病变是一种罕见的慢性眼内炎症性疾病。作者对该疾病的临床表现及其对治疗的反应进行了对比研究。

方法

我们选择了5例眼部有炎症的患者,这些患者在眼底检查中呈现出典型的多灶性脉络膜和色素上皮脱色素的黄白色斑块以及玻璃体炎症。

结果

所有患者在血管造影静脉期均显示早期低荧光斑变为高荧光,视网膜电图b波振幅降低,色觉有蓝黄色缺陷,并携带HLA - A 29抗原。我们记录到使用皮质类固醇和环孢素A治疗后视力和临床表现有所改善。

结论

尽管鸟枪弹样视网膜脉络膜病变在南欧是一种罕见的病症,但所呈现的病例使我们得出结论,早期诊断和适当治疗可大大改善这些患者的健康状况(《西班牙眼科协会档案》2002年;77:247 - 256)。

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