Xess A, Singh M, Raghwendra K H, Sharma H P, Shahi S K
Department of Microbiology, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna.
Indian J Pathol Microbiol. 2001 Jul;44(3):261-4.
PSA is emerging as the best marker in oncology and had a profound impact on all aspects of prostate cancer care. From clinically suspected prostate tumor, 395 serum samples were taken out and estimated for serum PSA. Among elevated serum PSA, 98 were correlated with histologic findings. 42(42.8%) cases were BHP among 98 cases and 78.7% had serum PSA level within 10 ng/ml. 5 patients (5.1%) had PIN histologically, 3(60%) of which had PSA level upto 10 ng/ml and 2(40%) had serum PSA upto 20 ng/ml. 51(52%) were adenocarcinoma prostate of different grades and PSA level varies from less than 10 ng/ml to more than 50 ng/ml which almost correlates with the tumor grades.
前列腺特异性抗原（PSA）正在成为肿瘤学中最佳的标志物，并对前列腺癌治疗的各个方面产生了深远影响。从临床怀疑患有前列腺肿瘤的患者中，采集了395份血清样本并检测血清PSA水平。在血清PSA水平升高的患者中，98例与组织学检查结果相关。98例中有42例（42.8%）为良性前列腺增生（BHP），78.7%的患者血清PSA水平在10 ng/ml以内。5例（5.1%）经组织学检查为前列腺上皮内瘤变（PIN），其中3例（60%）的PSA水平高达10 ng/ml，2例（40%）的血清PSA水平高达20 ng/ml。51例（52%）为不同分级的前列腺腺癌，PSA水平从低于10 ng/ml到高于50 ng/ml不等，这几乎与肿瘤分级相关。
