Murphy G J, Nicholson M L
Department of Surgery, Leicester General Hospital, Leicester, U.K.
Eur J Vasc Endovasc Surg. 2002 May;23(5):452-7. doi: 10.1053/ejvs.2002.1613.
diabetes mellitus is an increasingly common cause of end stage renal failure (ESRF) and the establishment of adequate permanent vascular access for dialysis is a major cause of morbidity and mortality in these patients. The aim of this study was to compare the availability of suitable vein, maturation rates, patency and complication rates of autogeneous elbow fistulas in diabetics and non-diabetics at a single centre where an autogeneous vein only policy is employed.
retrospective series.
two hundred and ninety-three elbow fistulas were attempted in 232 patients over a seven year period, [median age 60 years (range 14-94 years)], of which 210 were in non-diabetic and 83 were in diabetic patients. The diabetic group had a significantly higher proportion of male patients (p < 0.05), peripheral vascular disease and established ESRF.
there was a trend towards a higher technical success rate in the non-diabetic group (98% versus 93% p = 0.057). There was no significant difference between the primary failure rate, fistula maturation rate, revision rate or incidence of complications between the two groups. Diabetes had no effect on cumulative secondary fistula patency even when stratified for Type 1/Type 2 diabetes, female sex, old age or primary versus subsequent procedures.
diabetes mellitus has no significant detrimental effect on outcome following formation of autogeneous elbow fistulas for haemodialysis.
糖尿病是终末期肾衰竭(ESRF)日益常见的病因,为透析建立合适的永久性血管通路是这些患者发病和死亡的主要原因。本研究的目的是在一个仅采用自体静脉策略的单一中心,比较糖尿病患者和非糖尿病患者自体肘部动静脉内瘘的合适静脉可用性、成熟率、通畅率和并发症发生率。
回顾性系列研究。
在7年期间,对232例患者尝试建立了293个肘部动静脉内瘘,[中位年龄60岁(范围14 - 94岁)],其中210个在非糖尿病患者中,83个在糖尿病患者中。糖尿病组男性患者比例显著更高(p < 0.05),外周血管疾病和已确诊的ESRF患者比例也更高。
非糖尿病组的技术成功率有更高的趋势(98%对93%,p = 0.057)。两组之间的初次失败率、内瘘成熟率、修复率或并发症发生率无显著差异。即使按1型/2型糖尿病、性别、年龄或初次与后续手术分层,糖尿病对累积二次内瘘通畅率也没有影响。
糖尿病对自体肘部动静脉内瘘形成后用于血液透析的结局没有显著不利影响。