一名无免疫缺陷或血液系统疾病的儿童发生头孢曲松诱导的溶血性贫血。

Ceftriaxone-induced haemolytic anaemia in a child with no immune deficiency or haematological disease.

作者信息

Citak A, Garratty G, Ucsel R, Karabocuoglu M, Uzel N

机构信息

University of Istanbul, Institute of Child Health, Pediatric Emergency Department, Istanbul, Turkey.

出版信息

J Paediatr Child Health. 2002 Apr;38(2):209-10. doi: 10.1046/j.1440-1754.2002.00778.x.

DOI:10.1046/j.1440-1754.2002.00778.x

PMID:12031011

Abstract

A 5-year-old girl, with no underlying immune deficiency or haematologic disease, was treated with ceftriaxone for a urinary tract infection. After receiving ceftriaxone intramuscularly, massive haemolytic anaemia developed. Laboratory studies showed the presence of an antibody against ceftriaxone, and the findings reflected immune complex type haemolysis. High-dose corticosteroids appeared to be effective therapeutically.

摘要

一名5岁女童，无潜在免疫缺陷或血液系统疾病，因尿路感染接受头孢曲松治疗。肌肉注射头孢曲松后，出现大量溶血性贫血。实验室检查显示存在抗头孢曲松抗体，结果提示为免疫复合物型溶血。高剂量皮质类固醇似乎具有治疗效果。