Mannucci E, Tesi F, Ricca V, Pierazzuoli E, Barciulli E, Moretti S, Di Bernardo M, Travaglini R, Carrara S, Zucchi T, Placidi G F, Rotella C M
Chair of Metabolic Diseases, Section of Endocrinology, Department of Clinical Pathophysiology, University of Florence Medical School, Florence, Italy.
Int J Obes Relat Metab Disord. 2002 Jun;26(6):848-53. doi: 10.1038/sj.ijo.0801976.
Aim of this study was the assessment of the prevalence of eating disorders, and of eating disorder symptoms, in obese patients with type 2 diabetes, compared to non-diabetic subjects.
Three samples of individuals were studied: a series of 156 (76 male, 80 female) overweight and obese type 2 diabetic patients, aged 30-65 y, with a body mass index (BMI)>28 kg/m(2) (DM); a series of 192 (20 male, 172 female) obese (BMI>30 kg/m(2)) non-diabetic patients aged 30-65 y seeking treatment for weight loss (OC); and a non-clinical sample of 48 (22 male, 26 female) obese (BMI>30 kg/m(2)) subjects aged 30-65 y selected from the lists of two general practices (OP). Eating behavior was assessed using the Eating Disorder Examination (EDE 12.0D).
The prevalence of Binge Eating Disorder was lower than 5% in all the three samples. Median EDE scores in females were significantly higher in OC (3.0) and OP (3.4) than in DM (1.7), while diabetic patients showed higher scores on Restraint than both non-diabetic samples. Among diabetic patients, a significant correlation of EDE scores with HbA(1)c was observed.
Type 2 diabetes is unlikely to induce relevant eating disturbances in obese patients, apart from an increase in restraint. Abnormalities of eating attitudes and behavior are associated with an impairment of metabolic control.
本研究旨在评估2型糖尿病肥胖患者与非糖尿病受试者相比,饮食失调及饮食失调症状的患病率。
对三组个体进行了研究:一组为156例(76例男性,80例女性)年龄在30 - 65岁、体重指数(BMI)>28 kg/m²的超重和肥胖2型糖尿病患者(DM组);一组为192例(20例男性,172例女性)年龄在30 - 65岁、寻求减肥治疗的肥胖(BMI>30 kg/m²)非糖尿病患者(OC组);以及从两个普通诊所名单中选取的48例(22例男性,26例女性)年龄在30 - 65岁的肥胖(BMI>30 kg/m²)受试者的非临床样本(OP组)。使用饮食失调检查(EDE 12.0D)评估饮食行为。
在所有三个样本中,暴饮暴食症的患病率均低于5%。女性的EDE中位数得分在OC组(3.0)和OP组(3.4)显著高于DM组(1.7),而糖尿病患者在克制方面的得分高于两个非糖尿病样本。在糖尿病患者中,观察到EDE得分与糖化血红蛋白(HbA₁c)之间存在显著相关性。
除了克制增加外,2型糖尿病不太可能在肥胖患者中诱发相关的饮食紊乱。饮食态度和行为异常与代谢控制受损有关。