Sheen Jen
Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
Science. 2002 May 31;296(5573):1650-2. doi: 10.1126/science.1071883.
The past decade has seen substantial advances in knowledge of molecular mechanisms and actions of plant hormones, but only in the past few years has research on cytokinins begun to hit its stride. Cytokinins are master regulators of a large number of processes in plant development, which is known to be unusually plastic and adaptive, as well as resilient and perpetual. These characteristics allow plants to respond sensitively and quickly to their environments. Recent studies have demonstrated that cytokinin signaling involves a multistep two-component signaling pathway, resulting in the development of a canonical model of cytokinin signaling that is likely representative in plants. This Viewpoint outlines this general model, focusing on the specific example of Arabidopsis, and introduces the STKE Connections Maps for both the canonical module and the specific Arabidopsis Cytokinin Signaling Pathway.
在过去十年中，我们对植物激素的分子机制和作用的了解取得了重大进展，但直到最近几年，关于细胞分裂素的研究才开始蓬勃发展。细胞分裂素是植物发育中大量过程的主要调节因子，众所周知，植物发育具有异常的可塑性和适应性，以及恢复力和持续性。这些特性使植物能够对其环境做出敏感而快速的反应。最近的研究表明，细胞分裂素信号传导涉及一个多步骤的双组分信号通路，从而形成了一个可能在植物中具有代表性的细胞分裂素信号传导经典模型。本观点概述了这个通用模型，重点关注拟南芥的具体例子，并介绍了经典模块和特定的拟南芥细胞分裂素信号通路的STKE连接图谱。
