Russo G, Stefani S, Oliveri S
Institute of Microbiology, University of Catania, Italy.
J Chemother. 1991 Jan;3 Suppl 1:15-8.
Haemophilus influenzae and Branhamella catarrhalis can be considered inhabitants of the upper respiratory tract in humans. Although the pathogenetic role of H. influenzae cannot be discussed, the Authors report the mechanisms of pathogenicity of this microorganism; furthermore, they discuss the direct or indirect pathogenicity of B. catarrhalis in respiratory tract diseases and the ability of both microorganisms to produce beta-lactamases. H. influenzae and B. catarrhalis, together with S. pneumoniae, are the most common bacteria responsible for upper respiratory tract infections, namely otitis and sinusitis. The activity of these bacteria in the onset of otitis and sinusitis is reported.
流感嗜血杆菌和卡他莫拉菌可被视为人类上呼吸道的寄居菌。虽然流感嗜血杆菌的致病作用无需讨论，但作者报告了这种微生物的致病机制；此外，他们还讨论了卡他莫拉菌在呼吸道疾病中的直接或间接致病性以及这两种微生物产生β-内酰胺酶的能力。流感嗜血杆菌、卡他莫拉菌与肺炎链球菌一起，是引起上呼吸道感染（即中耳炎和鼻窦炎）最常见的细菌。文中报道了这些细菌在中耳炎和鼻窦炎发病过程中的活性。
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