Ottomano C, Frugoni S, Berlusconi A, Miseferi G, Mattina R, Anelli M
Istituto Geriatrico Pio Albergo Trivulzio, Milano, Italy.
J Chemother. 1991 Jan;3 Suppl 1:62-5.
997 strains isolated from clinical specimens arrived at the "Pio Albergo Trivulzio" microbiology laboratory were tested using disks of cefpodoxime, amoxicillin + clavulanic acid, cefaclor, cefuroxime, ofloxacin, cotrimoxazole, ceftriaxone and cefalexin. Gram-positive strains were tested also with erythromycin, while gram-negative bacteria were tested against aztreonam. Cefpodoxime overall activity was well above the effectiveness of the other oral cephalosporins and on the same order as ceftriaxone and ofloxacin. Cefpodoxime proved to be also more active than the combination amoxicillin-clavulanic acid.
从临床标本中分离出的997株菌株被送至“皮奥·阿尔贝戈·特里武尔齐奥”微生物实验室，使用头孢泊肟、阿莫西林+克拉维酸、头孢克洛、头孢呋辛、氧氟沙星、复方新诺明、头孢曲松和头孢氨苄的药敏纸片进行检测。革兰氏阳性菌株还使用红霉素进行检测，而革兰氏阴性菌则使用氨曲南进行检测。头孢泊肟的总体活性远高于其他口服头孢菌素，与头孢曲松和氧氟沙星相当。头孢泊肟也被证明比阿莫西林-克拉维酸组合更具活性。
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