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[一名患有奥尔布赖特遗传性骨营养不良患者的嗜酸性粒细胞性胃肠炎]

[Eosinophilic gastroenteritis in a patient with Albright's hereditary osteodystrophy].

作者信息

Bastida Eizaguirre M, Iturbe Ortiz De Urbina R I, Arto Urzainqui M J, de Las Muñecas Ibarrechebea J, Beltrán De Heredia P

机构信息

Servicio de Pediatría, Hospital Santiago Apóstol, Vitoria, Spain.

出版信息

An Esp Pediatr. 2002 Jun;56(6):576-8.

Abstract

Eosinophilic gastroenteritis is an uncommon chronic disease, of unknown cause, characterized by eosinophilic infiltration of the gastrointestinal tract, which is usually associated with peripheral blood eosinophilia. The symptoms of this complex disorder are variable, and frequently include abdominal pain, nausea, diarrhea, protein losing enteropathy and malabsorption. In general, patients can be successfully treated with corticosteroids, but relapses are common. We present the first case of a 6-year-old boy with Albright's hereditary osteodystrophy (Pseudohypoparathyroidism Ia) associated with eosinophilic gastroenteritis. Alternatives to traditional treatment with corticosteroids are discussed.

摘要

嗜酸性粒细胞性胃肠炎是一种病因不明的罕见慢性病,其特征为胃肠道嗜酸性粒细胞浸润,通常伴有外周血嗜酸性粒细胞增多。这种复杂病症的症状多样,常包括腹痛、恶心、腹泻、蛋白丢失性肠病和吸收不良。一般来说,患者使用皮质类固醇可成功治疗,但复发很常见。我们报告首例患有与嗜酸性粒细胞性胃肠炎相关的奥尔布赖特遗传性骨营养不良(假性甲状旁腺功能减退Ia型)的6岁男孩病例。并讨论了传统皮质类固醇治疗的替代方法。

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