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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Miller J P, Chait A, Lewis B

Clin Sci Mol Med. 1975 Dec;49(6):617-20. doi: 10.1042/cs0490617.

Cholesterol esterification has been studied in the plasma of subjects on diets rich in saturated or polyunsaturated fat. 2. The diet rich in polyunsaturated fat was associated with lower rates of plasma cholesterol esterification in vitro. The data suggest that there was a reduction of plasma lecithin-cholesterol acyltransferase activity as well as decreased ability of the lipoprotein substrates of the enzyme to support esterification. 3. On this diet, there was no change in the proportion of the plasma cholesterol esterified but the plasma cholesterol and triglyceride concentrations were reduced.

已对食用富含饱和脂肪或多不饱和脂肪饮食的受试者血浆中的胆固醇酯化情况进行了研究。2. 富含多不饱和脂肪的饮食与体外血浆胆固醇酯化率较低有关。数据表明，血浆卵磷脂 - 胆固醇酰基转移酶活性降低，以及该酶的脂蛋白底物支持酯化的能力下降。3. 在这种饮食情况下，血浆中胆固醇酯化的比例没有变化，但血浆胆固醇和甘油三酯浓度降低。

Miller J P, Chait A, Lewis B

Clin Sci Mol Med. 1975 Dec;49(6):617-20. doi: 10.1042/cs0490617.

Cholesterol esterification has been studied in the plasma of subjects on diets rich in saturated or polyunsaturated fat. 2. The diet rich in polyunsaturated fat was associated with lower rates of plasma cholesterol esterification in vitro. The data suggest that there was a reduction of plasma lecithin-cholesterol acyltransferase activity as well as decreased ability of the lipoprotein substrates of the enzyme to support esterification. 3. On this diet, there was no change in the proportion of the plasma cholesterol esterified but the plasma cholesterol and triglyceride concentrations were reduced.

已对食用富含饱和脂肪或多不饱和脂肪饮食的受试者血浆中的胆固醇酯化情况进行了研究。2. 富含多不饱和脂肪的饮食与体外血浆胆固醇酯化率较低有关。数据表明，血浆卵磷脂 - 胆固醇酰基转移酶活性降低，以及该酶的脂蛋白底物支持酯化的能力下降。3. 在这种饮食情况下，血浆中胆固醇酯化的比例没有变化，但血浆胆固醇和甘油三酯浓度降低。