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胸主动脉瘤的血管内治疗:综述

Endovascular treatment of thoracic aortic aneurysms: a review.

作者信息

Thurnher Siegfried A, Grabenwöger Martin

机构信息

Department of Radiology, University Hospital, Währinger Gürtel 18-20, 1097 Vienna, Austria.

出版信息

Eur Radiol. 2002 Jun;12(6):1370-87. doi: 10.1007/s00330-001-1277-y. Epub 2002 Mar 20.

Abstract

Open surgical repair is considered the traditional treatment for patients with thoracic aortic aneurysms (TAA). In view of the persistent perioperative mobidity and mortality, endovascular stent-graft placement as a minimally invasive and potentially safer treatment for aneurysm of the descending aorta was introduced in 1992. Since then, progress has been made and several institutions have substantiated the safety and effectiveness of stent grafts in the repair of descending TAAs or type-B aortic dissections. Currently, both custom-designed, home-made, and commercially available stent grafts are used. Prior to placement of the endoprosthesis, three major prerequisites must be considered: the localization and morphology of the aneurysm; the distal vascular access of sufficient size; and a limited tortuosity of the abdominal and thoracic aorta. Although short-term results are encouraging, severe complications, including paraplegia, cerebral strokes, and aortic rupture, have been encountered. The long-term durability of currently available stent-graft systems is nonexistent and material fatigue are of major concern to both surgeons and radiologists. Nevertheless, endovascular stent-graft placement could become the procedure of choice in a substantial number of patients with descending TAA.

摘要

开放手术修复被认为是胸主动脉瘤(TAA)患者的传统治疗方法。鉴于围手术期持续存在的发病率和死亡率,1992年引入了血管内支架移植物置入术,作为降主动脉瘤的一种微创且可能更安全的治疗方法。从那时起,取得了进展,几家机构证实了支架移植物在修复降主动脉瘤或B型主动脉夹层中的安全性和有效性。目前,定制的、自制的和市售的支架移植物都在使用。在放置内置假体之前,必须考虑三个主要前提条件:动脉瘤的定位和形态;足够大小的远端血管通路;以及腹主动脉和胸主动脉的有限迂曲度。尽管短期结果令人鼓舞,但仍遇到了严重并发症,包括截瘫、脑卒中和主动脉破裂。目前可用的支架移植物系统不存在长期耐久性,材料疲劳是外科医生和放射科医生主要关注的问题。然而,血管内支架移植物置入术可能会成为大量降主动脉瘤患者的首选治疗方法。

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