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既往子宫瘢痕处植入的两例异位妊娠的保守治疗

Conservative management of two ectopic pregnancies implanted in previous uterine scars.

作者信息

Haimov-Kochman R, Sciaky-Tamir Y, Yanai N, Yagel S

机构信息

Department of Obstetrics and Gynecology, Hadassah Medical Center, Hebrew University, Jerusalem, Israel.

出版信息

Ultrasound Obstet Gynecol. 2002 Jun;19(6):616-9. doi: 10.1046/j.1469-0705.2002.00719.x.

Abstract

Cesarean section scar pregnancy is rare. A variety of interventions have been implemented to terminate the pregnancy and preserve the uterus; however, the optimal treatment is unknown. We describe two cases of this rare condition diagnosed by transvaginal ultrasound. In the first case the diagnosis of an 8-week non-viable gestation in a uterine scar was made sonographically in a 40-year-old woman. The patient was treated with intramuscular methotrexate. Myometrial integrity was suggested both by ultrasound findings and laparoscopic findings. In the second case, an early cervicoisthmic pregnancy in a uterine scar was diagnosed by sonography in a 39-year-old woman. This patient was treated successfully with a full course of intramuscular methotrexate. Complete disappearance of the gestational sac took place 4 months following beta-human chorionic gonadotrophin normalization. Intramuscular methotrexate may be a treatment alternative for Cesarean section scar pregnancies.

摘要

剖宫产瘢痕妊娠较为罕见。为终止妊娠并保留子宫,已实施了多种干预措施;然而,最佳治疗方法尚不清楚。我们描述了两例经阴道超声诊断的这种罕见病症。第一例中,一名40岁女性经超声检查诊断为子宫瘢痕处8周不可存活妊娠。患者接受了肌肉注射甲氨蝶呤治疗。超声检查和腹腔镜检查结果均提示子宫肌层完整。第二例中,一名39岁女性经超声检查诊断为子宫瘢痕处早期宫颈峡部妊娠。该患者接受了全疗程肌肉注射甲氨蝶呤治疗,治疗成功。β-人绒毛膜促性腺激素恢复正常4个月后,妊娠囊完全消失。肌肉注射甲氨蝶呤可能是剖宫产瘢痕妊娠的一种治疗选择。

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