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半月板移植

Meniscal transplantation.

作者信息

Verdonk R

机构信息

Department of Orthopedic Surgery, Physical Medicine and Rehabilitation, Ghent University Hospital, Belgium.

出版信息

Acta Orthop Belg. 2002 Apr;68(2):118-27.

PMID:12050996
Abstract

The aims of a meniscal replacement are: 1) to reduce the pain experienced by some patients following meniscus resection; 2) to prevent the degenerative changes of cartilage and the changes in subchondral bone following meniscus resection; 3) to avoid or reduce the risk of osteoarthritis following meniscus resection; 4) to restore optimally the mechanical properties of the knee joint after meniscal resection. The results of meniscus transplantation have been studied in animals. There is no proof from these experiments that replacement of a meniscus can reduce the risk of arthritis, but there are indications that it can decrease the development of cartilage degeneration. In humans, the results of meniscus transplantation have been reported in several series of patients, operated with different techniques. There are no controlled studies of meniscus replacement in humans. In case of meniscal allograft implantation surgery should be minimally invasive, not sacrificing the original meniscal insertion points. It appears preferable to use an open technique in medial transplantation, whereas the arthroscopic approach appears to allow for easier lateral implantation.

摘要

半月板置换的目的包括

1)减轻部分患者半月板切除后所经历的疼痛;2)防止半月板切除后软骨的退行性改变以及软骨下骨的变化;3)避免或降低半月板切除后骨关节炎的风险;4)在半月板切除后最佳地恢复膝关节的力学性能。半月板移植的结果已在动物身上进行了研究。这些实验尚无证据表明半月板置换可降低关节炎风险,但有迹象表明其可减少软骨退变的发生。在人类中,已有多个系列患者接受不同技术手术的半月板移植结果报道。目前尚无关于人类半月板置换的对照研究。在同种异体半月板植入的情况下,手术应微创,不牺牲原半月板附着点。内侧移植似乎采用开放技术更佳,而关节镜入路似乎使外侧植入更容易。

相似文献

1
Meniscal transplantation.半月板移植
Acta Orthop Belg. 2002 Apr;68(2):118-27.
2
Joint degeneration following meniscal allograft transplantation in a canine model: mechanical properties and semiquantitative histology of articular cartilage.犬模型中同种异体半月板移植后的关节退变:关节软骨的力学性能和半定量组织学
Knee Surg Sports Traumatol Arthrosc. 2002 Mar;10(2):109-18. doi: 10.1007/s001670100227. Epub 2001 Aug 3.
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Prospective evaluation of concurrent meniscus transplantation and articular cartilage repair: minimum 2-year follow-up.半月板移植与关节软骨修复同期进行的前瞻性评估:至少2年随访
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[Laser-assisted induction of arthrosis].[激光辅助诱导关节病]
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引用本文的文献

1
Preparation and Characterization of an Optimized Meniscal Extracellular Matrix Scaffold for Meniscus Transplantation.用于半月板移植的优化半月板细胞外基质支架的制备与表征
Front Bioeng Biotechnol. 2020 Jul 9;8:779. doi: 10.3389/fbioe.2020.00779. eCollection 2020.
2
Meniscal Allograft Transplantation Does Not Prevent or Delay Progression of Knee Osteoarthritis.半月板同种异体移植不能预防或延缓膝关节骨关节炎的进展。
PLoS One. 2016 May 26;11(5):e0156183. doi: 10.1371/journal.pone.0156183. eCollection 2016.
3
Meniscus transplantation.
半月板移植
Curr Rev Musculoskelet Med. 2015 Dec;8(4):443-50. doi: 10.1007/s12178-015-9309-4.
4
Gene Therapy for Cartilage Repair.基因治疗在软骨修复中的应用。
Cartilage. 2011 Jul;2(3):201-25. doi: 10.1177/1947603510392914.
5
Preservation and sterilization methods of the meniscal allografts: literature review.半月板同种异体移植的保存和灭菌方法:文献综述
Cell Tissue Bank. 2014 Sep;15(3):307-17. doi: 10.1007/s10561-013-9396-7. Epub 2013 Sep 3.
6
Arthroscopic meniscal allograft transplantation with two tibia tunnels without bone plugs: evaluation of healing on MR arthrography and functional outcomes.不使用骨栓的双胫骨隧道关节镜下半月板同种异体移植:磁共振关节造影评估愈合情况及功能结果
Knee Surg Sports Traumatol Arthrosc. 2015 Jan;23(1):264-9. doi: 10.1007/s00167-013-2476-1. Epub 2013 Mar 19.
7
Assessment of apoptosis and MMP-1, MMP-3 and TIMP-2 expression in tibial hyaline cartilage after viable medial meniscus transplantation in the rabbit.兔内侧半月板移植后胫骨透明软骨细胞凋亡及 MMP-1、MMP-3 和 TIMP-2 表达的评估。
Arch Med Sci. 2012 Dec 20;8(6):1108-14. doi: 10.5114/aoms.2012.30947. Epub 2012 Oct 8.
8
The influence of pre-tensioning of meniscal transplants on the tibiofemoral contact area.半月板移植预张紧对胫股关节接触面积的影响。
Knee Surg Sports Traumatol Arthrosc. 2006 May;14(5):425-36. doi: 10.1007/s00167-005-0704-z. Epub 2005 Nov 22.
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[Arthroscopic meniscus surgery].[关节镜下半月板手术]
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