Featherstone J D B
Department of Preventive and Restorative Dental Sciences, University of California, Box 0758, 707 Parnassus Ave, San Francisco, CA 94143, USA.
Ned Tijdschr Tandheelkd. 2002 May;109(5):162-7.
Studies in our laboratories have demonstrated that specifically chosen CO2 laser treatment of dental enamel can markedly inhibit subsequent caries-like progression compared to controls in a laboratory model. Optimum caries inhibition in enamel appears to be achieved by pretreatments that produce surface temperatures in the range of 800-1200 degrees C. For clinical application the surface enamel heating must not lead to consequent pulp chamber temperature rises of > 4 degrees C. To meet these conditions a pulsed laser is required with a sufficiently high absorption coefficient (wavelength = 9.3 or 9.6 microns), pulse duration of 5-100 microseconds, 10-25 pulses per spot, repetition rate of 10-30 pulses per second, and low but effective fluence (approximately 1-5 J/cm2/pulse). A human intra-oral study has confirmed inhibition of caries progression in the human mouth. The clinical potential is good for caries preventive treatments by specific carbon dioxide laser conditions.
我们实验室的研究表明,在实验室模型中,与对照组相比,特定选择的二氧化碳激光对牙釉质的处理可显著抑制随后的龋样进展。牙釉质中的最佳防龋效果似乎是通过使表面温度达到800-1200摄氏度范围的预处理来实现的。对于临床应用,表面牙釉质加热不得导致牙髓腔温度随后升高超过4摄氏度。为满足这些条件,需要一种脉冲激光,其具有足够高的吸收系数(波长=9.3或9.6微米)、5-100微秒的脉冲持续时间、每点10-25个脉冲、每秒10-30个脉冲的重复频率以及低但有效的能量密度(约1-5焦耳/平方厘米/脉冲)。一项人体口腔内研究证实了在人口腔中龋病进展受到抑制。特定二氧化碳激光条件用于龋病预防治疗的临床潜力良好。