血栓性微血管病

Thrombotic microangiopathies.

作者信息

Halevy Daniel, Radhakrishnan Jai, Markowitz Glen, Appel Gerald

机构信息

Division of Nephrology, Department of Medicine, Columbia-Presbyterian Medical Center, New York, NY, USA.

出版信息

Crit Care Clin. 2002 Apr;18(2):309-20, vi. doi: 10.1016/s0749-0704(01)00004-5.

DOI:10.1016/s0749-0704(01)00004-5

PMID:12053836

Abstract

The thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation. Prognosis and treatment depend on the nature of the underlying disease.

摘要

血栓性微血管病（TMA）是一组与微血管病性溶血性贫血、血小板减少症和终末器官功能障碍相关的疾病。这些看似不同的实体具有涉及内皮损伤和血栓形成的共同致病机制。预后和治疗取决于潜在疾病的性质。