Marsh G R, Linnoila M
Psychopharmacology (Berl). 1979;66(1):99-104. doi: 10.1007/BF00431997.
Deanol (900 mg/day for 21 days) had no effect on learning a list of words when tested at weekly intervals. Tests of simple and complex reaction time and a test of continuous serial decoding of digits showed no enhancement with the drug. Several components of evoked potentials recorded from several scalp sites did show enhanced amplitude under drug treatment. These changes were not accompanied by changes in the EEG spectrum as are seen with some other psychoactive drugs. Deanol seems to be an ineffective treatment for the normal slowing of cognitive function seen in the normal elderly person or those elderly with only minimal cognitive decline and free of symptoms of dementia. Contrary to earlier reports, elderly persons were found to be able to benefit from warning signals in a complex reaction time task.
二甲氨基乙醇（每天900毫克，持续21天）在每周进行测试时，对学习一组单词没有影响。简单和复杂反应时间测试以及数字连续序列解码测试均未显示该药物有增强作用。从多个头皮部位记录的诱发电位的几个成分在药物治疗下确实显示出振幅增强。这些变化并未伴随脑电图频谱的变化，而其他一些精神活性药物则会出现这种情况。对于正常老年人或仅有轻微认知衰退且无痴呆症状的老年人中出现的认知功能正常减慢，二甲氨基乙醇似乎是一种无效的治疗方法。与早期报告相反，研究发现老年人在复杂反应时间任务中能够从警告信号中受益。
