Daud A, Munster P, Munster P, Spriggs D R
Department of Medicine, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.
Curr Treat Options Oncol. 2001 Apr;2(2):119-28. doi: 10.1007/s11864-001-0054-0.
The implementation of new drug treatments has improved the prognosis for advanced cancers of the cervix, uterus, and ovary. Platinum analogs are the most effective drugs in the treatment of ovarian cancer. Other drugs, such as oxaliplatin, have been proposed as a rational treatment of platinum refractory ovarian cancer. Epothilones are also being studied in clinical trials, as are histone deacetylase inhibitors. Several promising agents may soon receive Food and Drug Administration approval.
新药治疗的实施改善了晚期宫颈癌、子宫癌和卵巢癌的预后。铂类类似物是治疗卵巢癌最有效的药物。其他药物，如奥沙利铂，已被提议作为铂耐药卵巢癌的合理治疗药物。埃坡霉素正在临床试验中进行研究，组蛋白脱乙酰酶抑制剂也是如此。几种有前景的药物可能很快会获得美国食品药品监督管理局的批准。
