Moreno-Montañés J, Teutsch Ortlieb P, Rodríguez-Conde R, Corcóstegui Crespo I
Departamento de Oftalmología, Clínica Universitaria de Navarra, Pamplona, España.
Arch Soc Esp Oftalmol. 2002 Jun;77(6):309-13.
To determine the intraocular pressure (IOP) asymmetry in pseudoexfoliative (PSX) syndrome and glaucoma patients. To analyze the association between IOP asymmetry and clinical signs.
191 patients were prospectively studied, 75 (39.3%) with PSX syndrome and 116 (60.7%) with PSX glaucoma. IOP, visual field test, pigment and PSX material deposit in anterior segment structures were observed and compared between both eyes. The relation between IOP and clinical sign asymmetry was analyzed.
IOP asymmetry was less than 10 mm Hg in 138 cases (72.25%) and more than 10 mm Hg in 53 (27.75%) cases. The greatest asymmetry was found in unilateral PSX glaucoma patients (p= 0.001). Visual field test asymmetry was related with IOP asymmetry (p=0.0001). Also, IOP asymmetry was associated with pigment deposit in trabecular meshwork, in Sampaolesi line, and with pupillary atrophy asymmetry (p<0.05). PSX material deposit was not related with IOP asymmetry.
IOP asymmetry is greater in unilateral PSX glaucoma patients. The association between IOP and visual field test asymmetry found in this study suggests that PSX glaucoma is pressure dependent. IOP seems to be related with pigment deposit in anterior segment structures in PSX patients. However, this association was not found with PSX material deposit.
确定假性剥脱（PSX）综合征和青光眼患者的眼内压（IOP）不对称性。分析IOP不对称性与临床体征之间的关联。
对191例患者进行前瞻性研究，其中75例（39.3%）患有PSX综合征，116例（60.7%）患有PSX青光眼。观察并比较双眼的IOP、视野检查、前节结构中的色素和PSX物质沉积情况。分析IOP与临床体征不对称性之间的关系。
138例（72.25%）患者的IOP不对称性小于10 mmHg，53例（27.75%）患者的IOP不对称性大于10 mmHg。单侧PSX青光眼患者的不对称性最大（p = 0.001）。视野检查不对称性与IOP不对称性相关（p = 0.0001）。此外，IOP不对称性与小梁网、桑波雷西线中的色素沉积以及瞳孔萎缩不对称性相关（p < 0.05）。PSX物质沉积与IOP不对称性无关。
单侧PSX青光眼患者的IOP不对称性更大。本研究中发现的IOP与视野检查不对称性之间的关联表明PSX青光眼与眼压有关。在PSX患者中，IOP似乎与前节结构中的色素沉积有关。然而，未发现与PSX物质沉积有此关联。
