Martin Berdine R, Weaver Connie M, Heaney Robert P, Packard Patricia T, Smith David L
Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907-1264, USA.
J Agric Food Chem. 2002 Jun 19;50(13):3874-6. doi: 10.1021/jf020065g.
Two studies were conducted to measure calcium absorption from calcium sulfate fortified bread and three salts (calcium lactate, calcium carbonate, and calcium sulfate) in healthy premenopausal women using a crossover design. In study I, calcium fractional absorption levels from the three salts labeled with a stable isotope, 44Ca, were not significantly different (0.039-0.47) as determined by the fecal recovery method. In a second study, absorption of 45Ca from CaSO(4)-fortified labeled bread or labeled milk was measured in serum exactly 5 h postingestion. Fractional calcium absorption was slightly but significantly greater from fortified bread than from milk (mean within subject difference = 0.0675 +/- 0.016). Calcium sulfate is a bioavailable fortificant for white bread that compares favorably with milk and two other salts.