Satarić M V, Tuszyński J A
Faculty of Technical Sciences, 21000 Novi Sad, Serbia, Yugoslavia.
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 May;65(5 Pt 1):051901. doi: 10.1103/PhysRevE.65.051901. Epub 2002 Apr 29.
In this paper we examine the nonlinear dynamics of a DNA chain whose exciton modes are affected by regulatory proteins that may become bound to the DNA chain by hydrogen bonds. The dynamics of the DNA chain is described by the Peyrard-Bishop model. Since this model gives rise to large-amplitude broad oscillations of base pairs, we consider the impact of attached regulatory proteins on the so-called breathers or bubbles. Assuming that an ideal gas of bubbles may exist in the DNA chain at physiological temperatures we adopt a statistical approach to calculate the average size of base-pair stretching under the prevailing conditions.
在本文中，我们研究了DNA链的非线性动力学，其激子模式受到调节蛋白的影响，这些调节蛋白可能通过氢键与DNA链结合。DNA链的动力学由佩拉尔 - 毕晓普模型描述。由于该模型会引起碱基对的大幅度宽振荡，我们考虑附着的调节蛋白对所谓的呼吸子或气泡的影响。假设在生理温度下DNA链中可能存在气泡的理想气体，我们采用统计方法来计算在当前条件下碱基对拉伸的平均大小。
