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少数老年2型糖尿病患者尽管定期接受糖尿病视网膜病变的眼底照相筛查和激光治疗,最终仍会出现视力障碍。

A small number of older type 2 diabetic patients end up visually impaired despite regular photographic screening and laser treatment for diabetic retinopathy.

作者信息

Hansson-Lundblad Catharina, Holm Kristina, Agardh Carl-David, Agardh Elisabet

机构信息

Department of Ophthalmology, Malmö University Hospital, Malmö, Sweden.

出版信息

Acta Ophthalmol Scand. 2002 Jun;80(3):310-5. doi: 10.1034/j.1600-0420.2002.800315.x.

Abstract

PURPOSE

The present study describes the prevalence of visual impairment and blindness in a geographically defined population 8 years after the introduction of a screening programme in 1987 for early detection of sight-threatening diabetic retinopathy.

METHODS

Of 374 patients with diabetes, comprising 2.6% of the population in the study community, 72% were examined with fundus photography or biomicroscopy during 1994-95. These patients form the basis of this study. The screening programme was fulfilled by 93% of subjects, all of whom underwent ophthalmic examinations at least every other year. A total of 79 eyes in 52 patients received photocoagulation for macular oedema alone or in combination with severe non-proliferative or proliferative retinopathy.

RESULTS

Eight years after the implementation of the programme, only three patients, all with type 2 diabetes (diabetes diagnosed at or after 30 years of age), had visual acuity < or = 0.1. The total number of eyes with visual acuity < or = 0.5 was higher in insulin-treated type 2 diabetic patients (n = 20) than in those on oral treatment (n = 5) or diet treatment only (n = 1) (p = 0.006 in both cases). The only independent risk factor for visual impairment in eyes with sight-threatening retinopathy was age.

CONCLUSION

A small number of older type 2 diabetic patients end up with visual impairment due to unsuccessful photocoagulation of macular oedema.

摘要

目的

本研究描述了1987年引入一项筛查计划以早期发现威胁视力的糖尿病视网膜病变8年后,在一个地理界定人群中视力损害和失明的患病率。

方法

在研究社区的人群中,374例糖尿病患者占2.6%,其中72%在1994 - 1995年期间接受了眼底照相或生物显微镜检查。这些患者构成了本研究的基础。93%的受试者完成了筛查计划,所有受试者至少每隔一年接受一次眼科检查。共有52例患者的79只眼睛因单纯黄斑水肿或合并严重非增殖性或增殖性视网膜病变接受了光凝治疗。

结果

该计划实施8年后,仅3例患者视力≤0.1,均为2型糖尿病(30岁及以后诊断的糖尿病)。胰岛素治疗的2型糖尿病患者(n = 20)中视力≤0.5的眼睛总数高于口服治疗患者(n = 5)或仅接受饮食治疗的患者(n = 1)(两种情况p均 = 0.006)。在有威胁视力的视网膜病变的眼睛中,视力损害的唯一独立危险因素是年龄。

结论

少数老年2型糖尿病患者因黄斑水肿光凝治疗失败而导致视力损害。

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