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采用血管内支架移植物治疗主动脉夹层。

Treatment of aortic dissections with endovascular stent grafts.

作者信息

Greenberg Roy

机构信息

Department of Vascular Surgery, The Cleveland Clinic Foundation, OH 44195, USA.

出版信息

Semin Vasc Surg. 2002 Jun;15(2):122-7. doi: 10.1053/svas.2002.33090.

Abstract

The management of aortic dissections remains controversial. Knowledge regarding the extent and specific pathophysiology of each dissection is critical prior to intervention. Cross-sectional imaging techniques coupled with intravascular ultrasound or hemodynamic measurements are vital. In the setting of ischemia with significant true lumen compromise, the placement of a proximal endovascular graft has a high likelihood of dramatically improving the diameter of the true lumen, alleviating distal ischemia. Caution must be taken when branch vessels are involved in the dissection. Adequate true lumen flow with persistent end-organ ischemia is best handled with branch vessel stenting. Combined true lumen compresssion and branch vessel dissection requires both visceral vessel stenting and proximal endovascular grafting. Using these techniques, we have been able to achieve a mortality rate of less than 35% in a patient population that previously suffered mortality rates in excess of 50%. However, application of these technologies to asymptomatic or nonischemic dissections is not warranted outside the context of investigational trials.

摘要

主动脉夹层的治疗仍存在争议。在进行干预之前,了解每个夹层的范围和具体病理生理学至关重要。横断面成像技术结合血管内超声或血流动力学测量至关重要。在存在严重真腔受压导致缺血的情况下,近端血管内移植物的置入极有可能显著改善真腔直径,缓解远端缺血。当夹层累及分支血管时必须谨慎。对于存在持续终末器官缺血但真腔有足够血流的情况,最好采用分支血管支架置入术处理。真腔受压合并分支血管夹层需要同时进行内脏血管支架置入和近端血管内移植物置入。运用这些技术,我们已能够在之前死亡率超过50%的患者群体中实现死亡率低于35%。然而,在非试验性背景下,将这些技术应用于无症状或非缺血性夹层是不合理的。

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