Morimoto Noriko, Kawashiro Nobuko, Tsuchihashi Nobuaki, Shishiyama Fumiko
Department of Otolaryngology, National Center for Child Health and Development, Tokyo.
Nihon Jibiinkoka Gakkai Kaiho. 2002 May;105(5):570-6.
The most common form of nasal obstruction in neonates is soft tissue edema, but congenital bony nasal anomalies are recognized as an important cause of newborn airway obstruction. We reviewed 20 cases of congenital bony nasal abnormalties such as choanal atresia and nasal stenosis referred to National Children's Hospital between 1996 and 2001. Of the 20, 8 involved choanal atresia (6 bilateral and 2 unilateral) and 12 nasal stenosis (5 nasal cavity stenosis, 2 pyriform aperture stenosis and 5 unknown). Six cases of bilateral choanal atresia and 5 of 12 cases of the nasal stenosis presented severe airway distress. Most cases in respiratory distress required immediate surgical enlargement of nasal cavity and stenting with an endotracheal tube for 4 to 8 weeks. Of 12 with nasal stenosis, 5 with mild nasal obstruction were treated with nasal drops and 3 with mild airway distress required no treatment. Five of 7 (71%) with choanal atresia and 1 of 4 with nasal stenosis (25%) required restenosis of the nasal cavity after stent removal. Restenosis occurred more often in choanal atresia than in nasal atresia. Two of 5 with nasal restenosis required stenting for 1 to 2 months again and 1 of those was followed by stenting for more 4 months. Longer stenting did not prevent choanal from restenosis, however, no standard stenting protocol exists for neonates, highlighting the need for further study.
新生儿鼻阻塞最常见的形式是软组织水肿,但先天性鼻骨异常被认为是新生儿气道阻塞的一个重要原因。我们回顾了1996年至2001年间转诊至国立儿童医院的20例先天性鼻骨异常病例,如后鼻孔闭锁和鼻狭窄。在这20例病例中,8例为后鼻孔闭锁(6例双侧,2例单侧),12例为鼻狭窄(5例鼻腔狭窄,2例梨状孔狭窄,5例原因不明)。6例双侧后鼻孔闭锁和12例鼻狭窄中的5例出现严重气道窘迫。大多数呼吸窘迫病例需要立即进行鼻腔手术扩大并置入气管内导管支架4至8周。在12例鼻狭窄病例中,5例轻度鼻阻塞患者使用滴鼻剂治疗,3例轻度气道窘迫患者无需治疗。7例后鼻孔闭锁患者中有5例(71%)和4例鼻狭窄患者中有1例(25%)在支架取出后需要再次进行鼻腔再狭窄治疗。后鼻孔闭锁比鼻狭窄更常发生再狭窄。5例鼻腔再狭窄患者中有2例需要再次置入支架1至2个月,其中1例随后又置入支架4个月。然而,较长时间的支架置入并不能防止后鼻孔再狭窄,而且目前尚无针对新生儿的标准支架置入方案,这突出表明需要进一步研究。