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[分娩期间地西泮的使用]

[Use of diazepam during labor].

作者信息

Aguilar J, Iglesias M, Jimenez E, Cajide R, Ucieda R

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1975 Jul-Aug;4(5):747-58.

PMID:1206211
Abstract

The effect of diazepam has been watched and studied by continuing monitoring of the heart rate of the mother, the fetus and the newborn, as well as by studying the acid-base balance of the mother and the fetus and the newborn after doses of 20 mg of diazepam had been given to 40 normal labouring women. A good calming effect was found in 87 p. % of women and the remainder had an acceptable result. Both in the mother and in the fetus tachycardia resulted from injection of diazepam as well as a lessening in the frequency of changes in the heart rate. These two alterations were statistically significant (p less than 0.01) and appeared very soon after the administration of the diazepam. Later, no other effects could be found in the mother, the fetus or the newborn.

摘要

通过持续监测母亲、胎儿和新生儿的心率,以及在给40名正常分娩妇女注射20毫克地西泮后研究母亲、胎儿和新生儿的酸碱平衡,对地西泮的效果进行了观察和研究。在87%的妇女中发现了良好的镇静效果,其余的结果也可以接受。母亲和胎儿注射地西泮后均出现心动过速,且心率变化频率降低。这两种变化具有统计学意义(p<0.01),且在注射地西泮后很快出现。之后,在母亲、胎儿或新生儿身上未发现其他影响。

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