Facchin Gianella, Torre María H, Kremer Eduardo, Piro Oscar E, Castellano Eduardo E, Baran Enrique J
Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Montevideo, Uruguay.
J Inorg Biochem. 2002 Apr 28;89(3-4):174-80. doi: 10.1016/s0162-0134(02)00367-7.
Three new copper(II) complexes of stoichiometry [Cu(L-dipeptide)].nH(2)O, containing as ligands the dipeptides L-alanine-L-isoleucine, L-alanine-L-threonine and L-alanine-L-tyrosine were prepared. They were characterized by single crystal X-ray diffractometry, and electronic and infrared spectroscopy. In all cases, the Cu(II) cation has essentially the same elongated square pyramidal coordination, being equatorially cis coordinated by a N(2)O(2) arrangement of ligand atoms and axially by a carbonyl oxygen atom. The compounds show rather similar polymeric structures which resemble those recently reported for the [Cu(ala-val)] and [Cu(ala-phe)] complexes. The electronic and infrared spectra are briefly discussed on the basis of the structural peculiarities of the complexes. Superoxide dismutase (SOD)-like activity was also tested for the compounds.
制备了三种化学计量比为[Cu(L-二肽)].nH₂O的新型铜(II)配合物，其配体分别为二肽L-丙氨酸-L-异亮氨酸、L-丙氨酸-L-苏氨酸和L-丙氨酸-L-酪氨酸。通过单晶X射线衍射法、电子光谱和红外光谱对它们进行了表征。在所有情况下，Cu(II)阳离子基本上具有相同的拉长四方锥配位结构，在赤道平面上由配体原子的N₂O₂排列顺式配位，在轴向上由一个羰基氧原子配位。这些化合物显示出相当相似的聚合物结构，类似于最近报道的[Cu(ala-val)]和[Cu(ala-phe)]配合物的结构。根据配合物的结构特点简要讨论了电子光谱和红外光谱。还对这些化合物进行了超氧化物歧化酶(SOD)样活性测试。
