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关于马来亚森林鼠丝虫(布氏布氏丝虫)的研究:感染过程中的周期性和微丝蚴血症模式。

Studies on the Malayan forest rat filaria, Breinlia booliati: periodicity and microfilaraemic patterns during the course of infection.

作者信息

Yap E H, Ho B C, Singh M, Kang K L, Lim B L

出版信息

J Helminthol. 1975 Dec;49(4):263-9. doi: 10.1017/s0022149x00026262.

DOI:10.1017/s0022149x00026262
PMID:1206216
Abstract

Breinlia booliati exhibited nocturnal subperiodicity in its natural host, Rattus sabanus in contrast to experimentally infected laboratory-reared albine rats which showed irregular fluctuations of microfilariae throughout the 24 hour cycle. All the infected albino rats showed a prepatent period between 11-14 weeks postinoculation. Three patterns of microfilaraemia were discerned during the course of infection 38/49 rats displayed a single peak, 4/49 displayed 2 peaks about 12-15 weeks apart and 7/49 showed a sustained high plateau-like pattern of microfilaraemia. Cortisone had no effect on microfilarial levels when administered to rats near postpatency and some at postpatency.

摘要

布氏布氏丝虫在其天然宿主萨氏家鼠中表现出夜间亚周期性,这与实验感染的实验室饲养白化大鼠形成对比,后者在24小时周期内微丝蚴呈现不规则波动。所有感染的白化大鼠在接种后11 - 14周出现潜伏期。在感染过程中可识别出三种微丝蚴血症模式:49只大鼠中有38只呈现单峰,4只呈现两个相隔约12 - 15周的峰,7只呈现持续的高原样微丝蚴血症模式。当在接近潜伏期和一些处于潜伏期时给大鼠注射可的松,对微丝蚴水平没有影响。

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