Iannuzzi L, Molteni L, Di Meo G P, De Giovanni A, Perucatti A, Succi G, Incarnato D, Eggen A, Cribiu E P
National Research Council (CNR), IABBAM, Laboratory of Animal Cytogenetics and Gene Mapping, Naples, Italy.
Cytogenet Cell Genet. 2001;95(3-4):225-7. doi: 10.1159/000059349.
During normal cytogenetic investigations on the Chianina cattle (BTA) breed, a normal looking young bull was found to carry an abnormal Y chromosome which was a product of a reciprocal translocation between chromosomes Y and 9. This was revealed by both CBA- and RBG-banding techniques and was clearly confirmed by FISH-mapping analysis with IDVGA50 (which paints the complete Yq arm in a normal Y), as well as with AMD1, CGA, IGF2R (mapping to BTA9q16, BTA9q22 and BTA9q27-->q28, respectively) and SRY (mapping to normal BTAYq23). Analysis on sperm from four different samples revealed azoospermia in the carrier, indicating that the rcp(Y;9) induces sterility in the bull.
在对契安尼纳牛（BTA）品种进行常规细胞遗传学研究期间，发现一头外观正常的年轻公牛携带一条异常的Y染色体，它是Y染色体与9号染色体之间相互易位的产物。这通过CBA和RBG显带技术得以揭示，并用IDVGA50（可标记正常Y染色体上完整的Yq臂）以及AMD1、CGA、IGF2R（分别定位于BTA9q16、BTA9q22和BTA9q27→q28）和SRY（定位于正常BTAYq23）进行FISH图谱分析得到明确证实。对来自四个不同样本的精子进行分析发现，携带者存在无精子症，这表明rcp(Y;9)会导致公牛不育。
