Barkhausen J, Hunold P, Jochims M, Eggebrecht H, Sabin G V, Erbel R, Debatin J F
Universitätsklinikum Essen, Institut für Diagnostische und Interventionelle Radiologie, Germany.
Rofo. 2002 Jun;174(6):725-30. doi: 10.1055/s-2002-32226.
Purpose of our study was to compare the image quality of 3D-navigator steady state free precession (SSFP) and gradient echo (GE) sequences for magnetic resonance coronary angiography (MRCA) in volunteers and patients.
Following informed consent 8 volunteers and 12 patients were included into this study. In all subjects a 3D navigator MRCA of the right and the left coronary artery was performed with a SSFP (TR 3.9 ms, TE 1.7 ms, FA 65 degrees, bandwidth 540 Hz) and a GE (TR 5.8 ms, TE 2.2 ms, FA 25 degrees, bandwidth 200 Hz) sequence using a 1.5 T-MR-System (Magnetom Sonata, Siemens Erlangen). The slice thickness was 1.5 mm and the in-plane resolution was 0.9 x 0.7 mm (2) for all measurements.
The blood pool showed a significantly (p < 0.01) higher signal intensity on SSFP images (147 +/- 36) compared to GE images (103 +/- 36). Although noise increased with SSFP (9.3 +/- 1.4 versus 5.3 +/- 0.9), the contrast-to-noise ratio between myocardium and the coronaries was significantly (p < 0.01) higher on SSFP images (7.8 +/- 3.7 versus 3.4 +/- 3.3). The CNR between the coronaries and the epicardial fat showed no significant differences (12 +/- 5 versus 13 +/- 4).
The 3D-navigator SSFP sequence is a promising new technique for MRCA which improves the contrast between the coronaries and the myocardium and shortens the data acquisition compared to gradient-echo imaging.
本研究旨在比较三维导航稳态自由进动(SSFP)序列和梯度回波(GE)序列在志愿者和患者磁共振冠状动脉造影(MRCA)中的图像质量。
在获得知情同意后,8名志愿者和12名患者纳入本研究。所有受试者均使用1.5T磁共振系统(西门子公司的Magnetom Sonata,埃尔朗根),采用SSFP序列(重复时间3.9毫秒,回波时间1.7毫秒,翻转角65度,带宽540赫兹)和GE序列(重复时间5.8毫秒,回波时间2.2毫秒,翻转角25度,带宽200赫兹)对左右冠状动脉进行三维导航MRCA检查。所有测量的层厚均为1.5毫米,平面分辨率为0.9×0.7毫米²。
与GE图像(103±36)相比,血池在SSFP图像上的信号强度显著更高(p<0.01)(147±36)。尽管SSFP序列的噪声增加(9.3±1.4对5.3±0.9),但SSFP图像上心肌与冠状动脉之间的对比噪声比显著更高(p<0.01)(7.8±3.7对3.4±3.3)。冠状动脉与心外膜脂肪之间的对比噪声比无显著差异(12±5对13±4)。
三维导航SSFP序列是一种有前景的MRCA新技术,与梯度回波成像相比,它提高了冠状动脉与心肌之间的对比度,并缩短了数据采集时间。