Baurmann H, Sasaki K, Chioralia G, Hendrickson P, Hata N
Klin Monbl Augenheilkd. 1975 Nov;167(5):702-4.
The effects of laser coagulation on rat fundi were studied angiographically and with the fluorescence microscope. The coagulations were performed using constantly 300 mW and 0.2 second exposure time and 50 microns spot diameter. We observed the animals for 3 months, after which we could still observe dye diffusion by fluorescence angiography. With the fluorescence microscope we could localize these diffusions as originating from neovascularisation starting from the choroid. These new vessels penetrated subsequently into the exterior retinal layers. At the beginning of our observation time, the retinal vessels showed some sinuosities, dilatations and solitary stenosis, but no disturbance of circulation was demonstrable.
通过血管造影和荧光显微镜研究了激光凝固对大鼠眼底的影响。使用恒定的300毫瓦、0.2秒曝光时间和50微米光斑直径进行凝固。我们对动物观察了3个月,之后通过荧光血管造影仍可观察到染料扩散。通过荧光显微镜,我们可以将这些扩散定位为起源于脉络膜的新生血管。这些新血管随后穿透到视网膜外层。在我们观察期开始时,视网膜血管显示出一些迂曲、扩张和孤立性狭窄,但未发现循环障碍。