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TGF-beta antagonists: why suppress a tumor suppressor?

作者信息

Akhurst Rosemary J

机构信息

University of California-San Francisco, Mount Zion Cancer Research Institute, Room S231, Box 0875, 2340 Sutter Street, San Francisco, California 94143-0875, USA.

出版信息

J Clin Invest. 2002 Jun;109(12):1533-6. doi: 10.1172/JCI15970.

Abstract
摘要

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本文引用的文献

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Trends Mol Med. 2002;8(4 Suppl):S19-26. doi: 10.1016/s1471-4914(02)02306-7.
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Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.
J Cell Biol. 2002 Jan 21;156(2):299-313. doi: 10.1083/jcb.200109037. Epub 2002 Jan 14.
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TGF-beta signaling: positive and negative effects on tumorigenesis.
Curr Opin Genet Dev. 2002 Feb;12(1):22-9. doi: 10.1016/s0959-437x(01)00259-3.
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TGF-beta signaling in cancer--a double-edged sword.
Trends Cell Biol. 2001 Nov;11(11):S44-51. doi: 10.1016/s0962-8924(01)02130-4.
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TGF-beta signaling in tumor suppression and cancer progression.
Nat Genet. 2001 Oct;29(2):117-29. doi: 10.1038/ng1001-117.
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Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatoma.
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