Gillgren P, Brattström G, Djureen Mårtensson E, Frisell J, Palmgren J, Ringborg U, Hansson J
Department of Surgery, Stockholm Söder Hospital, SE-118 83 Stockholm, Sweden.
Br J Dermatol. 2002 Jun;146(6):1023-30. doi: 10.1046/j.1365-2133.2002.04783.x.
While sunlight is important in the aetiology of cutaneous malignant melanoma (CMM), the relationship between skin areas receiving intermittent or chronic sun exposure and the development of CMM has not been fully explored. There is a requirement for an improved method for more detailed site mapping and for analysis of tumour density in different areas of the skin in relation to the type of sun exposure, phenotypic traits and prognosis of patients with CMM.
To describe and demonstrate the use of EssDoll, a new computerized method to map and analyse tumour sites.
We have used the new software to analyse data on 2517 patients with 2608 primary CMMs.
The results obtained were consistent with previous data on the distribution of CMM in men and women. The distribution of CMM on the back was uneven, with the density on the upper back being twice that on the lower back.
The new methodology allows a more accurate mapping and analysis of skin tumour site, including determination of tumour density. This improves the possibility of analysing tumour site in relation to aetiological, phenotypic and prognostic parameters.
虽然阳光在皮肤恶性黑色素瘤（CMM）的病因学中很重要，但接受间歇性或慢性阳光照射的皮肤区域与CMM发生之间的关系尚未得到充分探索。需要一种改进的方法来进行更详细的部位映射，并分析皮肤不同区域的肿瘤密度与阳光照射类型、表型特征及CMM患者预后的关系。
描述并演示EssDoll这种用于映射和分析肿瘤部位的新计算机化方法的应用。
我们使用新软件分析了2517例患有2608个原发性CMM患者的数据。
所得结果与先前关于CMM在男性和女性中分布的数据一致。CMM在背部的分布不均匀，上背部的密度是下背部的两倍。
新方法能够更准确地映射和分析皮肤肿瘤部位，包括确定肿瘤密度。这提高了结合病因、表型和预后参数分析肿瘤部位的可能性。
