Wood W G, Hine I P, Mainwaring-Burton R W, Butler M J, Irving M H
Langenbecks Arch Chir. 1975;Suppl:53-8. doi: 10.1007/978-3-662-05557-1_11.
12 out of 13 patients who underwent cardiac surgery requiring extracorporeal circulation survived the operation. Arterial and venous catecholamines were measured throughout the operation. Larges rises in catecholamine levels were not seen although significant changes did occur in arteriovenous differences and also between samples at certain points in the operation. These facts do not agree with Lillehei's findings (3) and may reflect improvements in surgical technique, anaesthesia and the reduced time on bypass. However the lack of an overall measurable adrenergic response in terms of plasma catecholamine levels does agree with similar findings after open heart surgery (4) and during other surgical procedures (5).
13例接受需要体外循环的心脏手术的患者中,有12例术后存活。术中全程监测动脉和静脉血中的儿茶酚胺水平。尽管在动静脉差值以及手术某些阶段的样本之间确实发生了显著变化,但未观察到儿茶酚胺水平大幅升高。这些事实与利勒黑的研究结果(3)不一致,可能反映了手术技术、麻醉的改进以及体外循环时间的缩短。然而,就血浆儿茶酚胺水平而言,缺乏整体可测量的肾上腺素能反应这一情况与心脏直视手术后(4)以及其他外科手术过程中(5)的类似发现是一致的。