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[黏度降低对心肌梗死心肌血流及功能的影响]

[Effect of a decrease in viscosity on myocardial blood flow and function in myocardial infarct].

作者信息

Hottenrott C, Buckberg G D, Maloney J V

出版信息

Langenbecks Arch Chir. 1975;Suppl:75-7.

PMID:1207285
Abstract

In 5 dogs the effect of a decrease in blood viscosity on myocardial blood flow (radioactive microspheres) and left ventricular function (Sarnoff curves) following ligation of the left anterior descending coronary artery was tested. Moderate anaemia produced a significant increase in coronary blood flow to the total left ventricle (+ 100%) and to the ischemic area (+ 400%). Depressed left ventricular function after coronary ligation alone was restored when blood viscosity was lowered only slightly. Severe anaemia further increased coronary blood flow but left ventricular function worsened.

摘要

在5只狗身上,测试了降低血液粘度对结扎左冠状动脉前降支后心肌血流量(放射性微球法)和左心室功能(萨诺夫曲线)的影响。中度贫血使左心室整体的冠状动脉血流量显著增加(增加100%),缺血区域的血流量增加(增加400%)。仅在血液粘度略有降低时,单独冠状动脉结扎后降低的左心室功能就得以恢复。重度贫血进一步增加了冠状动脉血流量,但左心室功能恶化。

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