Heidenreich Axel, Olbert Peter, Engelmann Udo H
Klinik für Urologie and Kinderurologie, Philipps-Universität Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Eur Urol. 2002 Apr;41(4):392-7. doi: 10.1016/s0302-2838(02)00023-4.
Chronic testicular pain (CTP) is defined as uni- or bilateral, intermittent or continuous testicular discomfort of at least 3 months duration that interferes with the patient's daily activities and prompts him to seek medical advice is a rather common urological manifestation of chronic pain syndrome. Diagnosis and treatment of CTP has been a difficult and often unrewarding clinical situation. Success rates of conservative and surgical measures including epididymectomy and orchiectomy rarely exceed 55-73% and 10-40%, respectively. We report our experience on microsurgical testicular denervation as therapeutic option in CTP.
Following an extensive preoperative work-up (urine/semen cultures, transrectal ultrasound, testicular sonography, pain and orthopedic consultation) not revealing any pathologic abnormalities and a positive response to spermatic cord block, 35 patients underwent microsurgical testicular denervation. In brief, spermatic cord was dissected, vas deferens, cremasteric muscle and testicular vessels were separated. After identification of the testicular artery by application of vasodilatating agents using magnifying loops or the operating microscope, all structures besides the testicular artery, vas deferens and 1-2 lymphatic vessels were coagulated and transsected using bipolar diathermy.
After a mean follow-up of 31.5 months 34/35 (96%) patients are completely pain-free; no intra- or postoperative complications were encountered. No case of testicular atrophy or hydrocele formation was observed during postoperative follow-up.
Microsurgical testicular denervation results in reliable and reproducible excellent therapeutic success rates of 96% and should be integrated in the management of CTP at an early stage. High success rates require adequate and meticulous diagnostic work-up of the patients by spermatic cord block using saline as placebo and different local anaesthetics as an initial therapeutic armentarium predicting postoperative outcome.
慢性睾丸疼痛(CTP)被定义为单侧或双侧、间歇性或持续性的睾丸不适,持续时间至少3个月,干扰患者的日常活动并促使其寻求医疗建议,是慢性疼痛综合征相当常见的泌尿外科表现。CTP的诊断和治疗一直是困难且往往没有成效的临床情况。包括附睾切除术和睾丸切除术在内的保守和手术措施的成功率分别很少超过55 - 73%和10 - 40%。我们报告我们在显微外科睾丸去神经术作为CTP治疗选择方面的经验。
在进行广泛的术前检查(尿液/精液培养、经直肠超声、睾丸超声、疼痛及骨科会诊)未发现任何病理异常且对精索阻滞有阳性反应后,35例患者接受了显微外科睾丸去神经术。简而言之,解剖精索,分离输精管、提睾肌和睾丸血管。在使用放大环或手术显微镜应用血管扩张剂识别睾丸动脉后,除睾丸动脉、输精管和1 - 2条淋巴管外的所有结构均使用双极电凝进行凝固和横切。
平均随访31.5个月后,35例患者中有34例(96%)完全无痛;未遇到术中或术后并发症。术后随访期间未观察到睾丸萎缩或鞘膜积液形成的病例。
显微外科睾丸去神经术可产生可靠且可重复的高达96%的优异治疗成功率,应在CTP管理的早期阶段纳入。高成功率要求通过使用生理盐水作为安慰剂和不同局部麻醉剂进行精索阻滞对患者进行充分且细致的诊断检查,作为预测术后结果的初始治疗手段。