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腹腔镜下睾丸去神经术治疗慢性睾丸疼痛

Laparoscopic testicular denervation for chronic orchalgia.

作者信息

Cadeddu J A, Bishoff J T, Chan D Y, Moore R G, Kavoussi L R, Jarrett T W

机构信息

James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.

出版信息

J Urol. 1999 Sep;162(3 Pt 1):733-5; discussion 735-6. doi: 10.1097/00005392-199909010-00028.

Abstract

PURPOSE

No specific cause is identified in most cases of chronic orchialgia. Nonsurgical therapies, including management at a chronic pain clinic, are generally recommended. Only when multiple conservative measures fail are patients offered surgical intervention, such as orchiectomy. We evaluate laparoscopic testicular denervation as an organ preserving and minimally invasive surgical alternative.

MATERIALS AND METHODS

Since 1993, 9 patients with chronic orchialgia have undergone transperitoneal laparoscopic testicular denervation after nonsurgical modalities failed. Using 1, 10 mm. and 1 or 2, 5 mm. ports, the gonadal vessels were isolated circumferentially and divided cephalad to the vas deferens and its vasculature. Preoperative treatment modalities, morbidity and outcome were documented. A cord block provided temporary relief in all 9 patients. Analog scales were used to assess long-term pain relief (0 no pain to 100 worst pain) and activity levels (0 bedrest to 100 no restrictions).

RESULTS

Average symptom duration before laparoscopic testicular denervation was 4.1 years. Of 9 patients 8 had undergone prior scrotal surgery. Failed nonsurgical modalities included anti-inflammatory drugs in 7 patients, antibiotics in 6, pain clinic consultations in 4 and antidepressant medications in 2. Mean pain score decreased from 69.4 (range 35 to 90) preoperatively to 30.6 at a mean followup of 25.1 months. Excluding the 2 cases that had no pain relief (less than 10-point reduction), average pain score decreased from 69 to 19 postoperatively (mean reduction 71%). Activity levels improved in all cases. There were no significant complications, including testis atrophy. One patient who had no pain relief underwent subsequent hydrocelectomy for pain, which also failed.

CONCLUSIONS

Laparoscopic testicular denervation can provide significant long-term pain relief and appears to be a reasonable alternative in select cases with chronic orchialgia refractory to medical therapy. Larger series and prospective evaluations are necessary.

摘要

目的

大多数慢性睾丸疼痛病例未发现明确病因。一般建议采用非手术疗法,包括在慢性疼痛诊所进行治疗。只有在多种保守措施均失败时,才会对患者进行手术干预,如睾丸切除术。我们评估腹腔镜睾丸去神经术作为一种保留器官且微创的手术替代方案。

材料与方法

自1993年以来,9例慢性睾丸疼痛患者在非手术治疗失败后接受了经腹腹腔镜睾丸去神经术。使用1个10毫米和1或2个5毫米的端口,将性腺血管进行环形分离,并在输精管及其血管系统的上方进行切断。记录术前治疗方式、发病率和治疗结果。所有9例患者的精索阻滞均提供了临时缓解。使用视觉模拟评分法评估长期疼痛缓解情况(0分表示无疼痛,100分表示最严重疼痛)和活动水平(0分表示卧床休息,100分表示无限制)。

结果

腹腔镜睾丸去神经术前的平均症状持续时间为4.1年。9例患者中有8例曾接受过阴囊手术。失败的非手术疗法包括7例患者使用抗炎药、6例使用抗生素、4例进行疼痛诊所会诊以及2例使用抗抑郁药。平均疼痛评分从术前的69.4(范围35至90)降至平均随访25.1个月时的30.6。排除2例疼痛未缓解(疼痛减轻少于10分)的病例,术后平均疼痛评分从69降至19(平均降低71%)。所有病例的活动水平均有所改善。没有明显并发症,包括睾丸萎缩。1例疼痛未缓解的患者随后因疼痛接受了鞘膜积液切除术,但也失败了。

结论

腹腔镜睾丸去神经术可提供显著的长期疼痛缓解,对于某些药物治疗无效的慢性睾丸疼痛病例似乎是一种合理的替代方案。需要更大规模的系列研究和前瞻性评估。

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