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[正常及病理状态下人体支气管黏膜的扫描电子显微镜研究]

[Scanning electron microscopic study of human bronchial mucosa under normal and pathological conditions].

作者信息

Schaff Z, Kertes I, Lapis K, Nagy G, Csikós A

出版信息

Morphol Igazsagugyi Orv Sz. 1975 Oct;15(4):249-55.

PMID:1207699
Abstract

Scanning electronmicroscopic picture of the normal human bronchial mucosa and alterations of it in chronic bronchitis are described. According to the author's findings in chronic bronchitis the regular arrangement of cilia disappears, the number of them decreases and they become shortened with a club-like formation on the end. Focal destruction of the cilia can also be seen. In the epithelium of the mucosa number of the cells without cilia increases. This is a consequence of the destruction of the cilia on one hand, and increase of the number of mucus secreting goblet cells on the other. Alterations of the bronchial mucosa in chronic bronchitis revealed by scanning electron microscopy may play an important part in the pathogenesis and persistence of chronic bronchitis of different origine.

摘要

描述了正常人支气管黏膜的扫描电子显微镜图像以及慢性支气管炎时其变化。根据作者对慢性支气管炎的研究结果,纤毛的规则排列消失,数量减少且变短,末端呈棒状。还可见到纤毛的局灶性破坏。黏膜上皮中无纤毛细胞的数量增加。这一方面是纤毛破坏的结果,另一方面是分泌黏液的杯状细胞数量增加的结果。扫描电子显微镜显示的慢性支气管炎时支气管黏膜的变化可能在不同起源的慢性支气管炎的发病机制和持续存在中起重要作用。

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