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[Synthesis of O-substituted 6-oximes of 16alpha,17alpha-cyclohexanopregn-4-en-3,6,20-triones containing a tritium label at the 1,2-position].

作者信息

Shevchenko V P, Nagaev I Iu, Miasoedov N F, Kamernitskiĭ A V, Levina I S, Kulikova L E

机构信息

Institute of Molecular Genetics, Russian Academy of Sciences, pl. Akademika Kurchatova 2, Moscow, 123182 Russia.

出版信息

Bioorg Khim. 2002 May-Jun;28(3):258-60. doi: 10.1023/a:1015712505616.

Abstract

6-O-(3-Methoxycarbonylpropyl)- and 6-O-(3-carboxypropyl)oximes of 16 alpha,17 alpha-cyclohexanopregn-4-ene-3,6,20-trione labeled by tritium in position 1,2 were synthesized. When using homogenous catalysts, the molar radioactivity of the resulting preparations was 1.5-1.7 PBq/mol.

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