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新型高效合成N,N-二烷基氨基-O-烷基-2-(1-甲基-2-氧代亚丙基)磷酰肼肟。第3部分。

Novel and efficient synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido oximes. Part 3.

作者信息

Kumar Rajesh, Gupta Arvind K, Kaushik Mahabir P

机构信息

Process Technology Development Division, Defence R and D Establishment, Jhansi Road, Gwalior-474002 (MP), India.

出版信息

Molecules. 2007 Sep 21;12(9):2193-200. doi: 10.3390/12092193.

DOI:10.3390/12092193
PMID:17962736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6149135/
Abstract

A novel and efficient method has been developed for the synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido oximes 5. The reactions involve the condensation of diacetylmonoxime and N,N-dialkylamino-O- alkylphosphorohydrazides in the presence of activated silica and give the corresponding target oximes in excellent yields under mild conditions.

摘要

已开发出一种新颖且高效的方法来合成N,N-二烷基氨基-O-烷基-2-(1-甲基-2-氧代亚丙基)磷酰肼肟5。反应涉及二乙酰单肟与N,N-二烷基氨基-O-烷基磷酰肼在活化硅胶存在下的缩合反应，并在温和条件下以优异的产率得到相应的目标肟。

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本文引用的文献

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Novel and efficient synthesis of N,N-dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes--potential marine fish toxin analogues. Part 2.新型高效合成N,N-二烷基氨基和O-烷基苯基-2-(1-烷基/苯基-2-氧代亚丙基)膦酰肼肟——潜在的海洋鱼类毒素类似物。第2部分。
Molecules. 2007 Aug 2;12(8):1632-40. doi: 10.3390/12081632.
2
A novel and efficient synthesis of N,N-dialkylaminoisopropyl- and O-alkylisopropyl-2-(1-alkyl-2-oxopropylidene)phosphonohydrazido oximes--potential marine fish toxin analogues. Part 1.N，N-二烷基氨基异丙基-和O-烷基异丙基-2-（1-烷基-2-氧代亚丙基）膦酰肼肟的一种新颖高效合成方法——潜在的海洋鱼类毒素类似物。第1部分。
Molecules. 2007 Jul 9;12(7):1334-40. doi: 10.3390/12071334.
3
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