Aydoğan Umrah
Department of Pediatric Cardiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
Asian Cardiovasc Thorac Ann. 2002 Jun;10(2):124-8. doi: 10.1177/021849230201000207.
Transcatheter closure of patent ductus arteriosus using controlled-release coils was performed in 16 patients weighing < 10 kg. No embolization occurred. Procedure-related complications occurred in 3 patients (18.8%): massive femoral hemorrhage in 1 and femoral artery thrombosis in 2. The ductus recanalized in 1 of them because of mechanical hemolysis caused by streptokinase treatment. This was the only patient who underwent another occlusion procedure. Complete occlusion was achieved in 7 patients (43.8%) immediately, in 13 (81.2%) the following day, and in all 15 patients who had completed the 6-month follow-up. During follow-up, flow velocities between the left and the main pulmonary arteries and between the descending and the ascending aortae did not differ significantly. Flow velocity was > 2 m x sec(-1) in 3 patients in the left pulmonary artery and in 1 in the descending aorta. Protrusion of the coil was seen in 3 of these patients. Flow velocity was also high in the main pulmonary artery in the 4th patient. In conclusion, coil occlusion of ductus arteriosus is feasible in the small child, but no more than half a loop of the coil should be left at the pulmonary site. High flow velocity does not always mean obstruction.
对16例体重小于10kg的患儿采用缓释弹簧圈经导管封堵动脉导管未闭。未发生栓塞。3例(18.8%)出现与手术相关的并发症:1例发生股部大出血,2例发生股动脉血栓形成。其中1例因链激酶治疗导致机械性溶血,动脉导管再通。这是唯一接受另一次封堵手术的患儿。7例(43.8%)立即实现完全封堵,13例(81.2%)在次日实现完全封堵,所有15例完成6个月随访的患儿均实现完全封堵。随访期间,左肺动脉与主肺动脉之间以及降主动脉与升主动脉之间的血流速度无显著差异。3例患儿左肺动脉血流速度>2m×sec⁻¹,1例降主动脉血流速度>2m×sec⁻¹。其中3例可见弹簧圈突出。第4例患儿主肺动脉血流速度也较高。总之,弹簧圈封堵小儿动脉导管未闭是可行的,但在肺动脉侧留下的弹簧圈不应超过半圈。血流速度高并不总是意味着梗阻。